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Thursday, October 5, 2017

At the age of 66, US rock musician Tom Petty suffered cardiac arrest on Monday morning and died that evening at the UCLA Medical Center, Santa Monica in California, according to reports.

Petty, born in Gainesville, Florida in 1950, was best known as the lead singer of Tom Petty and the Heartbreakers. With the Heartbreakers and as a solo artist, Petty recorded a number of hit singles. He was one of the best-selling music artists of all time, selling more than 80 million records worldwide over the course of his career. He was inducted into the Rock and Roll Hall of Fame in 2002. Petty also co-founded the late 1980s supergroup the Traveling Wilburys.

Petty had a number of acting roles on film and television, playing a the mayor of a post-apocalyptic town in the 1997 Kevin Costner film The Postman. In 2002, Petty appeared on The Simpsons episode “How I Spent My Strummer Vacation” and from 2004 to 2009 voiced character Lucky on King of the Hill.

Petty married Jane Benyo in 1974, and they divorced in 1996. With Benyo, Petty had two daughters, Adria and Annakim. He married Dana York in 2001, acquiring a stepson named Dylan from her earlier marriage. He is also survived by a younger brother, Bruce, and a granddaughter, Everly.

Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

Thursday, June 7, 2007

Paris Hilton has been released from prison after serving only three days of her 23-day sentence, reports TMZ.com, though she will receive credit for five days (as the authorities in Los Angeles have counted Sunday evening and Thursday morning as a part of her sentence).

Reports indicate that Hilton was overcome by the stress of incarceration (credited as “medical reasons”), and reached an agreement to serve the remaining days of her sentence under house arrest. She will have to spend 40 days in house arrest, forced to wear a tracking ankle bracelet. The 26-year-old Hilton was released from the Los Angeles Jail Thursday and was placed into house arrest.

In January, the hotel heiress pleaded guilty to charges of alcohol-related reckless driving. In February, the California highway patrol caught her violating her three year probation. Hilton on Sunday entered the Century regional detention facility in Los Angeles, almost immediately after the MTV Movie Awards.

Monday, January 7, 2008

Christopher Lee McCuin, 25, from Tyler, Texas in the United States has been arrested after police found him possibly preparing to eat the body parts of his dead girlfriend, Jana Shearer aged 21. He was also charged with stabbing his ex-wife’s boyfriend, William Veasley, 42.

According to reports, Shearer’s mother was told by McCuin to “look in the garage” where she discovered the mutilated body of her daughter. She then flagged down a police officer on the road.

McCuin called 911 after the mother left the house. According to reports, he told the dispatcher that he was boiling Shearer’s body parts and preparing to eat them. When police got to his home, they discovered one of Shearer’s ears boiling in a pot, and an unnamed piece of her flesh on the kitchen table, with silverware placed beside it. The rest of her body had several “chunks” missing from it, according to the Tyler Morning Telegraph quoting Sheriff J.B. Smith of the Smith County Sheriff’s Department.

Police later found out that McCuin had stabbed his ex-wife’s boyfriend, and also broke into Tyler Custom Openings, a local business, sometime on Friday or Saturday. He started by going to Shearer’s home on Friday January 4 to have a discussion with her, but she was never seen alive again. Before stabbing Veasley, he beat Shearer “with a blunt object, multiple times” to death. On Saturday morning, he arrived at his ex-wife’s home and fought with Veasley, stabbing him. He is currently in critical condition at a local hospital.

McCuin then broke into the Tyler Custom Openings and then went to his mother’s house where he took her to his home to show her what he had done. Although McCuin was inside the house when police arrived, he was able to escape and was chased for a short distance before being caught again.

McCuin is currently being held on a US$2,000,000 bail at Smith County jail.

Monday, August 7, 2006

Dogs can be trained to detect early and late stages of lung and breast cancer accurately according to a study published by California scientists in the little-known scientific journal Integrative Cancer Therapies.

The study took place over the last five years at the Pine Street Foundation, a non-profit organization which conducts evidence-based research on integrative medicine (combining complementary and alternative medicine and mainstream medicine). Michael McCulloch and colleagues used three Labrador Retrievers and two Portuguese Water Dogs, both common pets, that received basic behavioral dog training. The researchers trained the dogs to lie down next to a sample from a cancer patient and to ignore other samples.

The samples used were breath samples from 55 patients with lung cancer and 31 with breast cancer — the two types of cancer with the highest mortality rates in the United States.

After the training phase, the dogs’ accuracy diagnosis was tested in a double-blind experiment. Among lung cancer patients, the sensitivity and specificity were 99% accurate and for breast cancer sensitivity was 88% and specificity 98%. Because these figures seem almost too good to be true, cancer experts are the same time baffled and skeptical. The authors of the study themselves also say replication of the study is needed.

Importantly, this was independent of the cancer stage, meaning the dogs were able to pick up the scent of cancer in its early stages. This is important because in many cases, the success of any treatment depends on early diagnosis. However, the researchers don’t believe this will lead to the use of dogs in the clinic soon, rather they want to find out which chemicals are actually sensed by the canines, because they could be used in laboratory assays. “It’s not like someone would start chemotherapy based on a dog test,” Dr. Gansler of the American Cancer Society said, “They’d still get a biopsy.”.

The researchers were inspired by anecdotal reports about dogs detecting cancer. In 1989, a British women consulted with her family physician because her Dalmatian kept licking a mole on her leg. At biopsy it showed to be malignant melanoma. When diagnosed too late this form of cancer has a poor survival rate, but in this case early surgery was made possible, and the women survived. Prior studies showed that breath samples from patients with lung cancer or breast cancer contain distinct biochemical markers. This provides a basis for the hypothesis that some cancer types produce volatile chemicals that dogs could smell. A study published in the British Medical Journal already proved that dogs could use their exquisite sense of smell to detect bladder cancer in urine samples, but they were only correct in 41% of cases, and another study provided preliminary evidence that dogs could detect melanomas.

This doesn’t mean you can show your breasts to your dog and it will tell you if you have cancer, other physicians caution, and scientists do not advise people to train their dogs to sniff for cancer. Unresolved issues from the study include the fact that subjects were required to breathe deeper than normal, so it’s not sure whether dogs can smell cancer in normal breath. Also, whether this is a permanent skill that would be retained by dogs was not tested.

Finally, there are concerns that could arise over liability issues: who would be responsible when the dog makes a mistake?

Current detection methods for both lung and breast cancer are not flawless. For lung cancer, chest X-ray and sputum cytology (detecting cancer cells in coughed up fluid) fail to detect many early cases, and CT scan produces many false-positive results unless combined with expensive PET scans. Although it might be comparing apples and oranges, a $2.5 million CT scanner has an accuracy of 85 to 90%. Mammography also produces false-positive results, and it may be difficult in women with dense breast tissue. As such, another type of “pet”-scan, using dogs as a biological assay, might prove feasible for screening if supported by further research. Current tests are also expensive so the use of dogs for preliminary cancer testing could prove to be an affordable alternative for countries in the developing world.

Saturday, October 14, 2006

Over the weekend, millions of Americans faced the new ban of online gambling.

The legislation was attached by Rep. Bill Frist to the Port Security bill.

Many of the public companies that offer online gambling have been quick to react and give their outlooks on the legislature. Party Gaming and 888 among others have said that they will shut down all U.S. operations if President Bush signs the bill into law. This sent online gambling stocks tumbling with Party Gaming leading the way with a 55% decrease in market value.

The people involved are awaiting to see what happens over the next few weeks.

Wednesday, December 10, 2008

According to East African Seafarers’ Assistance Programme Kenyan chapter head, Andrew Mwangura, the Greek freighter MV Captain Stephanos and all its 19 crew, consisting of 17 Filipinos, one Chinese and a Ukrainian, had been released late Monday, after 78 days in captivity. It was unclear, however, if any ransom was paid. The Philippine Department of Foreign Affairs said that “there are [still] 91 Filipino seafarers on board six ships still with Somali pirates.”

Somali pirates seized the Bahamas-flagged vessel on September 21 near the Horn of Africa, as the bulk carrier, was cruising in the Gulf of Aden en route and transporting coal to Europe. The captors locked the crew inside the vessel and they were not fed well. The vessel is now headed to Italy and will sail from there to Greece, to meet the ship owners.

Reuters reported that “a surge in attacks at sea this year in the busy Gulf of Aden and Indian Ocean off Somalia has pushed up insurance costs, brought the gangs tens of millions of dollars in ransoms, and prompted foreign warships to rush to the area.”